The lining of the gastrointestinal tract (GI tract) is made of a single layer of cells attached to each other with Gap-Junctions, also known as tight junctions. A gap-junction essentially keeps food particles and microbes inside the GI tract so that it won’t to leak into the body before being digested properly. Without Gap junctions the Digestive tube would basically be a tube with many hole in it!  digestive system

 

A recent study on industrial food additives such as added glucose, added salt, emulsifiers, organic solvents, added gluten, microbial transglutaminase, and nanoparticles has shown that all of these food additives damage the Gap-junctions.  It is no wonder then that in developed countries, where process food is consumed more than other places, rates of autoimmune disease are much higher.

here is a link to the original article:

http://www.ncbi.nlm.nih.gov/pubmed/25676324